© BrainNet Europe II
BrainNet Europe is a "Network of Excellence" funded by the European Commission in the 6th Framework Program "Life Science" (LSHM-CT-2004-503039). It consists of 19 established brain banks across Europe and is coordinated by the Centre for Neuropathology and Prion Research Ludwig-Maximilians-University Munich, Germany.
Participant 18: Hospices Civils de Lyon
Lyon institution's expertise
Over the last decades Lyon has been internationaly recognized as an important research center in both fundamental and clinical neurosciences. The Neurological Hospital of Lyon is one of the greatest neurology and neurosurgery centers in Europe, with more than 12 000 patients consulting/year, 400 beds for hospitalisation, more than 1000 cases of surgery for brain tumours. The Neurological Hospital includes or is surrounded by 18 research laboratories constituting the Lyon Federative Institut for Neurosciences (IFNL) and belonging to the Claude Bernard University (4 medical schools), the INSERM, the CNRS, and the Lyon Hospitals.
The Laboratory of Neuropathology has a long history since it was among the first created in France (1967) and possesses a large collection of cases. Its activity can be summarized as follows :
There is a close relationship between neuropathology and biochemistry (neurochemistry unit)
There is also a close relationship between neuropathologists and neurologists, the later being highly involved, together with the neurochemists, in the development of tissue preservation within the Neurobiotec Bank. With the support of patients associations, the number of autopsies is increasing.
The Neurological Hospital has a large experience in banking: Neurobiotec, created in 1997, is one of the first biological resource centers in France. The bank collects brain tumours, muscle biopsy samples, blood, urine and CSF. Patient consents are required. Samples are frozen, cultured, and/or fixed according to validated protocols. Clinical summaries and pictures are associated with samples. High security system and recording informations have been established.
The connection of the Neuropathology and Biochemistry laboratories with fundamental research is tight:
In the future:
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