© BrainNet Europe II
BrainNet Europe is a "Network of Excellence" funded by the European Commission in the 6th Framework Program "Life Science" (LSHM-CT-2004-503039). It consists of 19 established brain banks across Europe and is coordinated by the Centre for Neuropathology and Prion Research Ludwig-Maximilians-University Munich, Germany.
|WP07 - Donor Program|
The main objectives of the WP 7 are:
Scientific research of neurological or psychiatric diseases relies strongly on readily available human CNS tissue, which can only be obtained in sufficient quantities through post mortem retention of brain, spinal cord and nerve tissue. Availability of such tissue becomes ever more problematic as the autopsy rates decline steadily throughout Europe.
Alternative methods for tissue procurement, such as donor programs potentially form a great resource for extremely well-documented research materials and have considerable scientific and ethical advantages. The open nature of donor recruitment promotes public understanding and support for scientific research. The voluntary element safeguards the principles of autonomy and self-determination of the participating individuals.
Scientifically the donor programs carry a great advantage. Due to the short post-mortem delay and a customized clinical characterization, tissue collected through such programs results in research material of higher quality. A short post-mortem delay, achieved by a rapid autopsy donor program, preserves the cellular and molecular components of the material, making it exceptionally suitable for sensitive research techniques applied for genomic and proteomic analyses, staining or post mortem cell-line and tissue cultures.
Customized clinical characterization of the research material can be achieved by the follow-up of the living person registered as a donor.
In order to set up and maintain a successful donor program, longstanding commitment of affiliated institutions and funding organizations is indispensable.
previous / next