© BrainNet Europe II
BrainNet Europe is a "Network of Excellence" funded by the European Commission in the 6th Framework Program "Life Science" (LSHM-CT-2004-503039). It consists of 19 established brain banks across Europe and is coordinated by the Centre for Neuropathology and Prion Research Ludwig-Maximilians-University Munich, Germany.
|WP18 - Protein Preservation|
Protein degradation is a progressive and consistent phenomenon following death; abnormal protein folding, and protein degradation may occur in the agonal period as well. Yet protein integrity is crucial in the study of physiological and pathological cellular events. Therefore, information regarding the influence of agonal state, post-mortem delay, and storage of the nervous tissue is a preliminary requirement for a serious approach to the study of molecular mechanisms involved in the normal and abnormal function of the nervous system.
Among other objectives, this work package aims at:
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